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Looking Back On Tech, Startups, And VC In 2018

Haystack

And as more economies worldwide seek to shift their investment strategies offshore and seek out technology, hubs like Silicon Valley and Shanghai, among others, have reaped the benefits. More and more angels will be minted as the 2019 IPO class emerges. Hundreds of new micro funds somehow keep getting into the market.

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Lessons Learned: Customer Development Engineering

Startup Lessons Learned

There were a lot of questions about outsourcing/offshoring and startups. It seems many startups these days are under a lot of pressure to outsource their development organization to save costs. So we had to completely throw that code away, including all of its beatiful tests and specs. Talk about waste.

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Update on America’s Slipping Global Competitiveness– Implications for Intellectual Property Development of Senate Bill 515

Pascal's View

The cost of filing patents has increased dramatically. The cost of enforcing patents has gone through the roof. monopolists) and low cost producers (e.g., offshore companies with lower labor costs, fixed currencies and weaker environmental standards).

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Reinventing Life Science Startups–Therapeutics and Diagnostics

Steve Blank

Yet during those same 60 years, rather than decreasing, the cost of getting a new drug approved by the FDA has increased 80 fold. Yep, it cost 80 times more to get a successful drug developed and approved today than it did 60 years ago. Pharma companies are staggering under the costs. And medical device innovation in the U.S.

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Innovation, Change and the Rest of Your Life

Steve Blank

For life sciences it was the Genentech IPO in 1980 that proved to investors that life science startups could make them a ton of money. Continuous innovation requires the imagination and courage to challenge the initial hypotheses of your current business model (channel, cost, customers, products, supply chain, etc.) The founders.

Restful 231