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The 10 Best U.S. Cities to Start a Business in for 2016

Up and Running

Government Requirements. Charlotte, NC. Coming in at number seven overall, Charlotte also ranks as the second best city after Grand Rapids when it comes to growth in number of small businesses. If you are interested in starting a business in Charlotte, check out these resources: Charlotte Business Resources: Starting a Business.

St. Louis 105
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43 Entrepreneurs Explain Why They Started Their Businesses

Hearpreneur

Soon, we were getting referrals in states (outside of Phoenix, where I was at the time) and instead of telling those clients no (because I realized if I said no, they would find someone else) I flew to the different areas, reached out to my network and would hire and train sitters in those cities. 6) Lack of information in an industry.